An inquiry into the causes ad effects of the variolae vaccinae, a disease discovered in some of the western counties of England, particularly Gloucestershire, and known by the name of the cow pox.

London, printed for the author, by S. low, and sold by Law [etc.] 1798.

"Jenner established the fact that a "vaccination" or inoculation with vaccinia (cow pox) lymph matter protects against small pox. He performed his first vaccination on May 14, 1796. The above work, describing 23 successful vaccinations, announced to the world one of the greatest triumphs in the history of medicine. Jennerian vaccination soon superseded the protective inoculation of material from human cases of small pox, which had previously been in vogue. What is probably the first mention of anaphylaxis appears on p. 13 of the pamphlet. As a result of the success of Jenner's vaccine natural smallpox was eradicated. The official declaration was made by the World Health Organization on May 8, 1980" (Morton's Medical Bibliography, Fifth Edition, Edited by Jeremy M. Norman)..

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